Module 2: Complications: Compatibility, acute & long term transfusion risks & errors

The content on this page is specific for 2021-2022 Transfusion Camp.

Reminder:

• Materials and YouTube links must not be used or distributed outside of Transfusion Camp without the consent of the Transfusion Camp organizers.
• Materials are ​provided for educational purposes only. They are not intended to be a substitute for the advice of a physician and should be assessed in the context of the applicable medic​al, legal and ethical requirements in any individual case.

Module 2 Overview

Acute Non-infectious Reactions (Dr. Christine Cserti-Gazdewich)
Acute & Delayed Transfusion Transmitted Infections (Dr. Steven Drews)
Delayed Non-infectious Reactions (Dr. Waseem Anani)
Informed Consent (Dr. Katerina Pavenski)
Alloimmunization & Anemia in Pregnancy (Dr. Nadine Shehata)
Pre-operative Patent Blood Management (Dr. Yulia Lin)
Seminar 2A: Labile Component Reactions
Seminar 2B: “Delayed or Derivative” Transfusion Reactions

See General Information Program Brochure document for detailed agenda.

Pre-readings

1.    Carson JL, Triulzi DJ, Ness PM. Bloody easy 4: Indications for and Adverse Effects of Red-Cell Transfusion. N. ENGL J MED;377(13):1261-1278.

2.    Sunnybrook Health Sciences Centre. REACT. 2016 JUN; PR15156.

3.    Webb J, Delaney M. Red Blood Cell Alloimmunization in the Pregnant Patient. Transfus Med Rev. 2018 Jun;32:213-219.

4.    Richards T, Rao Baikady R, Clevenger B, Butcher A, Abeysiri S, Chau M, et al. Preoperative intravenous iron to treat anaemia before major abdominal surgery (PREVENTT):  randomized double-blind, controlled trial. Lancet. 2020; 396: 1353–61.

5.    Shah A, Palmer AJR, Klein AA. Strategies to minimize intraoperative blood loss during major surgery. BJS 2020; 107: e26-e38.

6.    Padhi S, Kemmis-Betty S, Rajesh S, Hill J, Murphy MF, On behalf of the Guideline Development Group. Blood transfusion: summary of NICE guidance. BMJ 2015;351:h5832 doi: 10.1136/bmj.h5832.

The following readings are reference material only:

1.    Delaney M, Wendel S, Bercovitz RS, Cid J, Cohn C, Dunbar NM, et al. Prevention, diagnosis, and treatment of transfusion reactions: Evidence-based review & clinical guidelines. Supplement to: Transfusion reactions: prevention, diagnosis, and treatment. Lancet. 2016 Dec;388(10061):2825-2836.

2.    Haass K, Sapiano MRP, Savinkina A, Kuehnert MJ, Basavaraju SV. Transfusion-transmitted Infections reported to the National Healthcare Safety Network Hemovigilance Module. Transfus Med Rev. 2019 Apr;33(2):84-91.

3.    Leblanc JF, Germain M, Delage G, O’Brien S, Drews SJ, Lewin A. Risk of transmission of severe respiratory syndrome Coronavirus-2 by transfusion: A literature review. Tranfs. 2020; p.21.

4.    O’Brien SF, Yi QL, Fan W, Scalia V, Goldman M, Fearon MA. Residual risk of HIV, HCV, and HBV in Canada. Transfus Apher Sci. 2017 Mar;56(3):389-391.

5.    Vossoughi SR, Mccauley R, Sazama K, Fung MK. Attitudes, Practices, and Training on Informed Consent for Transfusions and Procedures: A Survey of Medical Students and Physicians. Am J Clin Pathol. 2015 Aug;144:315-321.

6.    Froessler B, Murphy E, Hodyl N. Iron deficiency in PREVENTT. Lancet. 2021 Feb 20;397(10275):668. doi: 10.1016/S0140-6736(21)00227-0. PMID: 33610207.

7.    Thrombosis Canada. NOACS/DOACS: Management of bleeding. 2020 Apr. 6p.

8.    Thrombosis Canada. NOACS/DOACS: Perioperative management of antiplatelet therapy. 2020 Apr. 5p.

Lectures

1.    Acute Non-Infectious Reactions (Dr. Christine Cserti-Gazdewich)

2.    Acute & Delayed Transfusion Transmitted Infections (Dr. Steven Drews)

3.    Delayed Non-infectious Reactions (Dr. Waseem Anani)

4.    Informed Consent (Dr. Katerina Pavenski)

5.    Alloimmunization & Anemia in Pregnancy (Dr. Nadine Shehata)

6.    Pre-operative Patient Blood Management (Dr. Yulia Lin)

To view the lectures recordings on YouTube, open the video and click on the playlist icon in the top right-hand corner to select your lecture of interest.

If you wish to submit your questions about any of the lectures to your seminar lead prior to the seminar session, you may submit them here.

Module 2 Highlights

Transfusion Camp for non-physician prescribers 2021-2022 Module 2: Complications: Compatibility, Acute & Long Term Transfusion Risks & Errors, summary highlights.

Seminars

Answers for the seminars are posted below once the Transfusion Camp module is completed.

Review the Guide for Participating in Seminars prior to attending the seminars.

Seminar 2A: Labile Component Reactions

Seminar 2B: “Delayed or Derivative” Transfusion Reaction