Module 2: Transfusion reactions & complications

The content on this page is specific for January - February 2023 Transfusion Camp.

Reminder:

• Materials and YouTube links must not be used or distributed outside of Transfusion Camp without the consent of the Transfusion Camp organizers.
• Materials are ​provided for educational purposes only. They are not intended to be a substitute for the advice of a physician and should be assessed in the context of the applicable medic​al, legal and ethical requirements in any individual case.

Module 2 Overview

Acute Non-infectious Reactions (Dr. Christine Cserti-Gazdewich)
Acute & Delayed Transfusion Transmitted Infections (Dr. Steven Drews)
Informed Consent (Dr. Marissa Laureano)
Alloimmunization & Anemia in Pregnancy (Dr. Nadine Shehata)
Pre-operative Patent Blood Management (Dr. Yulia Lin)
Seminar 2A: Transfusion Reactions
Seminar 2B: Consent and Patient Blood Management

See General Information Program Brochure document for detailed agenda.

Lectures

To view the lectures recordings on YouTube, open the video and click on the playlist icon in the top right-hand corner to select your lecture of interest.

Please note: To effectively participate in the seminars, you must watch the recorded lectures prior to attending the seminars. 

1.    Acute Non-Infectious Reactions (Dr. Christine Cserti-Gazdewich)

2.    Acute & Delayed Transfusion Transmitted Infections (Dr. Steven Drews)

3.    Informed Consent (Dr. Marissa Laureano)

4.    Alloimmunization & Anemia in Pregnancy (Dr. Nadine Shehata)

5.    Pre-operative Patient Blood Management (Dr. Yulia Lin)

If you wish to submit your questions about any of the lectures to your seminar lead prior to the seminar session, you may submit them here.

Module 2 Lecture Highlights

Transfusion Camp for nurse practitioners Module 2: Transfusion reactions & complications summary highlights.

Pre-readings

1.    Carson JL, Triulzi DJ, Ness PM. Bloody easy 4: Indications for and Adverse Effects of Red-Cell Transfusion. N. ENGL J MED;377(13):1261-1278.

2.    AABB Quick Reference Guide: NHSN Hemovigilance Module; Adverse Reactions Definitions. 2021 MAR.

3.    Webb J, Delaney M. Red Blood Cell Alloimmunization in the Pregnant Patient. Transfus Med Rev. 2018 Jun;32:213-219.

4.    Richards T, Rao Baikady R, Clevenger B, Butcher A, Abeysiri S, Chau M, et al. Preoperative intravenous iron to treat anaemia before major abdominal surgery (PREVENTT):  randomized double-blind, controlled trial. Lancet. 2020; 396: 1353–61.

5.    Shah A, Palmer AJR, Klein AA. Strategies to minimize intraoperative blood loss during major surgery. BJS 2020; 107: e26-e38.

6.    Bulle EB, Klanderman RB, Pendergrast J, Cserti-Gazdewich C, Callum J, Vlaar APJ. The recipe for TACO: A narrative review on the pathophysiology and potential mitigation strategies of transfusion-associated circulatory overload. Blood Rev. 2021 Oct 2:100891. doi: 10.1016/j.blre.2021.100891. PMID: 34627651

7.    TTISS-ON. Acute Transfusion Reaction Chart. 2020 OCT.

8.    Lin, Y, Preoperative anemia screening clinics. Hematology. 2019 Dec 6, 2019(1): 570-576.

The following readings are reference material only:

1.    Delaney M, Wendel S, Bercovitz RS, Cid J, Cohn C, Dunbar NM, et al. Prevention, diagnosis, and treatment of transfusion reactions: Evidence-based review & clinical guidelines. Supplement to: Transfusion reactions: prevention, diagnosis, and treatment. Lancet. 2016 Dec;388(10061):2825-2836.

2.    Froessler B, Murphy E, Hodyl N. Iron deficiency in PREVENTT. Lancet. 2021 Feb 20;397(10275):668. doi: 10.1016/S0140-6736(21)00227-0. PMID: 33610207.

3.    Thrombosis Canada. NOACS/DOACS: Management of bleeding. 2020 Apr. 6p.

4.    Thrombosis Canada. NOACS/DOACS: Perioperative management of antiplatelet therapy. 2020 Apr. 5p.

Seminars

Answers for the seminars are posted below once the Transfusion Camp module is completed.

Review the Guide for Participating in Seminars prior to attending the seminars.

Seminar 2A: Transfusion Reactions

Seminar 2B: Consent and Patient Blood Management