Recent Updates

Modified on: 
Nov 12, 2020

Anti-Le, commonly anti-Lea, Leb, or Leab, are antibodies directed to antigens of the Lewis blood group system. The Lewis antigens are glycoproteins that are found on the surface of many cells and secreted in various body fluids. As such, Lewis, along with ABO and H are sometimes referred to as “histo-blood groups,” given the fact they are present on many different tissue types.

Transfusion
Modified on: 
Nov 12, 2020

Anti-Kpa is an antibody directed to an antigen of the Kell blood group system. The Kell antigens are located on the red blood cell transmembrane glycoprotein known as CD238, and consist of a large group of 35 antigens. Some of these antigens are highly immunogenic, and after the ABO and Rh blood group systems, they are the most common immunogenic group for red blood cells. However, Anti-Kpa itself is extremely rare.

Transfusion
Modified on: 
Nov 12, 2020

Authors: Danielle Meunier, MD; Sophia Peng, MD; and Gwen Clarke, MD, FRCPC
Publication date: September 2019
Primary target audiences: Medical laboratory technologists (MLT) in a hospital laboratory, transfusion medicine physicians

Transfusion
Modified on: 
Nov 12, 2020

Authors: Danielle Meunier, MD; Sophia Peng, MD; and Gwen Clarke, MD, FRCPC
Publication date: September 2019
Primary target audiences: Medical laboratory technologists (MLT) in a hospital laboratory, transfusion medicine physicians

Transfusion
Modified on: 
Nov 12, 2020

Authors: Danielle Meunier, MD; Sophia Peng, MD; and Gwen Clarke, MD, FRCPC
Publication date: September 2019
Primary target audiences: Medical laboratory technologists (MLT) in a hospital laboratory, transfusion medicine physicians

Transfusion
Modified on: 
Oct 30, 2020
  • Alloimmunization is common in patients with sickle cell disease and may complicate transfusion therapy.
  • Patient phenotyping and prophylactic matching to reduce alloimmunization is recommended.
  • Transfusion requirements and the presence or absence of red cell antibodies influence recommendations on the extent of phenotyping for patients with sickle cell disease.
  • Limited evidence exists on the impact of the storage age of blood in this population, but provision of fresh units imposes significant challenges and may compromise availability of optimally phenotype-matched units.
Transfusion
Modified on: 
Oct 22, 2020

Author: Rob Romans 
Publication date: March 2019  

The primary target audience for this educational resource: Medical Laboratory Technologist (MLT) in the hospital laboratory, Prescribers of cryoprecipitates. 

Transfusion
Modified on: 
Oct 22, 2020

The short storage period for platelet units results in very challenging inventory management, and many platelet units are discarded.

Transfusion
Modified on: 
Oct 20, 2020

Author: Rob Romans, ART, BSc
Online publication date: August 2019

Background

In August 2018, the National Advisory Committee on Blood and Blood Products (NAC) endorsed the document “Guidance on Platelet Transfusion for Patients With Hypoproliferative Thrombocytopenia” published by the International Collaboration for Transfusion Medicine Guidelines (ICTMG).1, 2, 3

Transfusion
Modified on: 
Sep 30, 2020

Decisions about blood safety need to take numerous factors into account, such as risks, benefits, costs, ethical issues, and stakeholder perspectives.

ABO has developed a unique framework to help blood service operators streamline the process and make responsible decisions that lead to the greatest good. Whether the blood safety decision to be made is small or large in scale, this framework can help to organize the process and to assure the quality of the information used to make the decision. 

Transfusion

Pages