Topic Teaching: T-cell adoptive immunotherapy; creating and administering living drugs

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Event details

Presented by:

Dr. Jean-Sébastien Delisle
Associate Director - Hematopoietic Cell Transplantation
Canadian Donation and Transplantation Research Program (CDTRP)
Clinical Associate Professor, Université de Montréal

Objectives:

1.   To recognize the current and future clinical indications for T-cell adoptive immunotherapy.
2.   To understand the principles of clinical-grade T-cell manufacturing and validation.
3.   To gain (or consolidate) operational knowledge of T-cell biology relevant to T-cell immunotherapy.

References:

1.   Developing neoantigen-targeted T cell-based treatments for solid tumors.  Yamamoto TN, Kishton RJ, Restifo NP.  Nat Med. 2019 Oct 7. doi: 10.1038/s41591-019-0596-y. [Epub ahead of print] Review.  PMID: 31591590.
2.   Updates on CAR T-cell therapy in B-cell malignancies.  Jacoby E, Shahani SA, Shah NN.  Immunol Rev. 2019 Jul;290(1):39-59. doi: 10.1111/imr.12774. Review.  PMID: 31355492.
3.   Infusion of cytotoxic T lymphocytes for the treatment of viral infections in hematopoetic stem cell transplant patients.  Baugh KA, Tzannou I, Leen AM.  Curr Opin Infect Dis. 2018 Aug;31(4):292-300. doi: 10.1097/QCO.0000000000000456. Review.  PMID: 29750672.

 

Note: The session is a self-approved group learning activity (Section 1) as defined by the Maintenance of Certification program of The Royal College of Physicians and Surgeons of Canada.

To register for the LearnTransfusion series, send an email to learn.transfusion@blood.ca with  “Weekly Transfusion Medicine Seminars” in the subject line. Include your name and complete e-mail address in the body of the e-mail, and confirm that you would like to register for the LearnTransfusion series. You will then receive weekly email notifications of upcoming series events with details on how to join the webinars (e.g., call-in number and a link to register for the webinar).

The LearnTransfusion series is the seminar component of the Areas of Focused Competency (AFC)-Diploma Program in Transfusion Medicine. The series, organized by Canadian Blood Services is also open to all practitioners in the field of Transfusion Medicine. Through a series of regular webinars, trainees and practitioners are exposed to various scientific, technical and clinical aspects of transfusion medicine.