Topic Teaching: Something is better than nothing - the use of pre-hospital plasma and whole blood

Presented by:

Mark Yazer, MD
Professor of Pathology, University of Pittsburgh
Visiting Professor in Pathology, Tel Aviv University
Adjunct Professor of Clinical Immunology, University of Southern Denmark
Associate Medical Director, Centralized Transfusion Service

Objectives:

1.    Appreciate the renaissance of whole blood in the modern resuscitation of massively bleeding patients.
2.    Appreciate the serological safety of administering group O whole blood to non-O recipients.
3.    Understand some of the latest efficacy data following the administration of LTOWB.

References:

1.    JN Seheult, MN Stram, J Sperry, PC Spinella, DJ Triulzi, MH Yazer. In silico model of the dilutional effects of conventional component therapy versus whole blood in the management of massively bleeding adult trauma patients.  Transfusion 2019;59:146-158.
2.    JN Seheult, V Anto, LH Alarcon, JL Sperry, DJ Triulzi, and MH Yazer. Clinical outcomes among low-titer group O whole blood recipients compared to recipients of conventional components in civilian trauma resuscitation.  Transfusion 2018;58:1838-1845.
3.    JL Sperry, FX Guyette, JB Brown, MH Yazer, DJ Triulzi, B Early, P Adams, B Daley, R Miller, B Harbrecht, J Claridge, H Phelan, W Witham, T Duane, T Putman, L Alarcon, T Xu, C Calloway, B Zuckerbraun, M Neal, R Forsythe, TR Billiar,  D Yealy, AB Peitzman, Mazen Zenati for the PAMPer Study Group. Prehospital Air Medical Plasma Following Trauma and Hemorrhagic Shock: The PAMPer Cluster Randomized Trial.  New England Journal of Medicine 2018;379:315-326.

Note: The session is a self-approved group learning activity (Section 1) as defined by the Maintenance of Certification program of The Royal College of Physicians and Surgeons of Canada.

To register for the LearnTransfusion series, send an email to learn.transfusion@blood.ca with  “Weekly Transfusion Medicine Seminars” in the subject line. Include your name and complete e-mail address in the body of the e-mail, and confirm that you would like to register for the LearnTransfusion series. You will then receive weekly email notifications of upcoming series events with details on how to join the webinars (e.g., call-in number and a link to register for the webinar).

The LearnTransfusion series is the seminar component of the Areas of Focused Competency (AFC)-Diploma Program in Transfusion Medicine. The series, organized by Canadian Blood Services is also open to all practitioners in the field of Transfusion Medicine. Through a series of regular webinars, trainees and practitioners are exposed to various scientific, technical and clinical aspects of transfusion medicine.