Topic Teaching: Consumptive Thrombohaemorrhagic Disorders

Presented by:

Theodore (Ted) Earl Warkentin
MD, BSc(Med), FRCPC, FACP, FRCP (Edin)
Professor, Pathology and Molecular Medicine
Division: Hematology (Transfusion Medicine)
McMaster University

Objectives:

1.   What are useful screening blood tests for evaluation of thrombocytopenia and/or coagulopathy?
2.   What is “PTT confounding”?
3.   What is the pathogenesis of GI bleeding in aortic stenosis (Heyde’s syndrome)?

References:

1.   Skeith L, Baumann Kreuziger L, Crowther MA, Warkentin TE. A practical approach to evaluating postoperative thrombocytopenia. Blood Adv 2020 Feb 25; 4 (4): 776-783. doi: 10.1182/bloodadvances.2019001414. [PMID: 32097460]
2.   Warkentin TE. Anticoagulant failure in coagulopathic patients: PTT confounding and other pitfalls. Exp Opin Drug Saf 2014 Jan; 13 (1): 25-43. Epub 2013 Aug 23. [PMID: 23971903]
3.   Warkentin TE, Moore JC, Anand SS, Lonn EM, Morgan DG. Gastrointestinal bleeding, angiodysplasia, cardiovascular disease, and acquired von Willebrand syndrome. Transfus Med Rev 2003; 17 (4): 272-286. [PMID: 14571395]

Note: The session is a self-approved group learning activity (Section 1) as defined by the Maintenance of Certification program of The Royal College of Physicians and Surgeons of Canada.

To register for the LearnTransfusion series, send an email to learn.transfusion@blood.ca with  “Weekly Transfusion Medicine Seminars” in the subject line. Include your name and complete e-mail address in the body of the e-mail, and confirm that you would like to register for the LearnTransfusion series. You will then receive weekly email notifications of upcoming series events with details on how to join the webinars (e.g., call-in number and a link to register for the webinar).

The LearnTransfusion series is the seminar component of the Areas of Focused Competency (AFC)-Diploma Program in Transfusion Medicine. The series, organized by Canadian Blood Services is also open to all practitioners in the field of Transfusion Medicine. Through a series of regular webinars, trainees and practitioners are exposed to various scientific, technical and clinical aspects of transfusion medicine.