LearnTransfusion Series

Journal Club: Cord-Blood Transplantation in Patients with Minimal Residual Disease.

10 janvier, 2017 | 12:00 - 13:00 (EDT)



Dr. Shadiya AlKhan
Transfusion Medicine Physician Trainee
University of British Columbia

Event objectives:

  • Background information including current CBS practice for cord blood availability and collection
  • The article presentation
  • Critical appraisal of the article


  1. Riccardo Saccardi et al, Impact of cord blood banking technologies on clinical outcome: a Eurocord/Cord Blood Committee (CTIWP), European Society for Blood and Marrow Transplantation and NetCord retrospective analysis, Transfusion August 2016
  2. Filippo Milano et al, Cord-Blood Transplantation in Patients with Minimal Residual Disease, Nejm September 2016
  3. Laughlin MJ, Barker J, Bambach B, Koc O, Rizzieri D, Wagner J et al. Hematopoietic engraftment and survival in adult recipients of umbilical-cord blood from unrelated donors. N Engl J Med 2001; 344: 1815–1822.
  4. Laughlin MJ, Eapen M, Rubinstein P, Wagner J, Zhang M, Champlin R et al. Outcomes after transplantation of cord blood or bone marrow from unrelated donors in adults with leukemia. N Engl J Med 2004; 351: 2265–2275.
  5. AABB Technical manual
  6. CBS cord blood related SOPs
  7. Wood BL. Flow cytometric monitoring of residual disease in acute leukemia. Methods Mol Biol 2013;999:123-36.
  8. Walter RB, Buckley SA, Pagel JM, et al. Significance of minimal residual disease before myeloablative allogeneic hematopoietic cell transplantation for AML in first and second complete remission. Blood 2013;122:1813-21.

The LearnTransfusion series is the seminar component of the Areas of Focused Competency (AFC)-Diploma Program in Transfusion Medicine. The series, organized by Canadian Blood Services is also open to all practitioners in the field of Transfusion Medicine. Through a series of regular webinars, trainees and practitioners are exposed to various scientific, technical and clinical aspects of transfusion medicine. For more information about the LearnTransfusion series and how to register visit LearnTransfusion series.