Recent Updates

Modified on: 
Nov 14, 2019

Authors: Danielle Meunier, MD; Sophia Peng, MD; and Gwen Clarke, MD, FRCPC
Publication date: September 2019
Primary target audiences: Medical laboratory technologists (MLT) in a hospital laboratory, transfusion medicine physicians

Transfusion
Modified on: 
Nov 14, 2019

Authors: Danielle Meunier, MD; Sophia Peng, MD; and Gwen Clarke, MD, FRCPC
Publication date: September 2019
Primary target audiences: Medical laboratory technologists (MLT) in a hospital laboratory, transfusion medicine physicians

Transfusion
Modified on: 
Nov 14, 2019

Authors: Danielle Meunier, MD; Sophia Peng, MD; and Gwen Clarke, MD, FRCPC
Publication date: September 2019
Primary target audiences: Medical laboratory technologists (MLT) in a hospital laboratory, transfusion medicine physicians

Transfusion
Modified on: 
Nov 14, 2019

Authors: Danielle Meunier, MD; Sophia Peng, MD; and Gwen Clarke, MD, FRCPC
Publication date: September 2019
Primary target audiences: Medical laboratory technologists (MLT) in a hospital laboratory, transfusion medicine physicians

Transfusion
Modified on: 
Nov 14, 2019

Authors: Danielle Meunier, MD; Sophia Peng, MD; and Gwen Clarke, MD, FRCPC
Publication date: September 2019
Primary target audiences: Medical laboratory technologists (MLT) in a hospital laboratory, transfusion medicine physicians

Transfusion
Modified on: 
Nov 14, 2019

Authors: Danielle Meunier, MD; Sophia Peng, MD; and Gwen Clarke, MD, FRCPC
Publication date: September 2019
Primary target audiences: Medical laboratory technologists (MLT) in a hospital laboratory, transfusion medicine physicians

Transfusion
Modified on: 
Nov 14, 2019
Authors: Gwen Clarke, MD, FRCPC; Jacqueline Côté, MLT; and Debra Lane, MD, FRCPC
Publication date: October 2019
Primary target audiences: Medical laboratory technologists (MLTs) in a hospital laboratory, transfusion medicine physicians

Key points

  • Anti-M is rarely clinically significant.
  • Patients with anti-M should receive red blood cell units crossmatch compatible by IAT or equivalent using IgG antihuman globulin for transfusion.
Transfusion
Modified on: 
Nov 13, 2019

Anti-Le, commonly anti-Lea, Leb, or Leab, are antibodies directed to antigens of the Lewis blood group system. The Lewis antigens are glycoproteins that are found on the surface of many cells and secreted in various body fluids. As such, Lewis, along with ABO and H are sometimes referred to as “histo-blood groups,” given the fact they are present on many different tissue types.

Transfusion
Modified on: 
Nov 13, 2019

Anti-Kpa is an antibody directed to an antigen of the Kell blood group system. The Kell antigens are located on the red blood cell transmembrane glycoprotein known as CD238, and consist of a large group of 35 antigens. Some of these antigens are highly immunogenic, and after the ABO and Rh blood group systems, they are the most common immunogenic group for red blood cells. However, Anti-Kpa itself is extremely rare.

Transfusion
Modified on: 
Nov 7, 2019

All blood transfused in Canada is collected from volunteer donors. To ensure the safety of the blood products, donors are carefully screened against an extended list of eligibility criteria. In addition, the donated blood is tested to identify the donor’s blood group and to detect blood group antibodies and transfusion-transmissible pathogens. Donor eligibility criteria and testing also benefit the donors by, for example, reducing potential blood donation-related health risks.

Transfusion

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