LearnTransfusion Series

Journal Club: Role of IV iron in pregnancy: Journal Club reviewing "Safety and effectiveness of intravenous iron sucrose versus standard oral iron therapy in pregnant women with moderate-to-severe anaemia in India: a multicentre, open-label, phase 3..."

When: 
February 11, 2020 | 12:00PM to 1:00PM (EDT)
Where: 

Toronto/Webinar

Presented by:

Dr. Aggrey Dhabangi
Transfusion Medicine Physician Trainee
McMaster University

Objectives:

1.    Describe the global burden of iron deficiency (ID) and iron deficiency anemia (IDA) in Pregnancy.
2.    Describe the impact ID and IDA in Pregnancy to the mother and fetus/infant.
3.    Highlight the approach to clinical management of ID and IDA in Pregnancy.
4.    Review and critically appraise methods and results from the study.
5.    Discuss the pros and cons of conducting interim analyses for phase III Clinical trials.

References:

1.    Safety and effectiveness of intravenous iron sucrose versus standard oral iron therapy in pregnant women with moderate-to-severe anaemia in India: a multicentre, open-label, phase 3, randomised, controlled trial.  Neogi SB, Devasenapathy N, Singh R, Bhushan H, Shah D, Divakar H, Zodpey S, Malik S, Nanda S, Mittal P, Batra A, Chauhan MB, Yadav S, Dongre H, Saluja S, Malhotra V, Gupta A, Sangwan R, Radhika AG, Singh A, Bhaskaran S, Kotru M, Sikka M, Agarwal S, Francis P, Mwingak K, Baswal D.  Lancet Glob Health. 2019 Dec; 7(12):e1706-e1716. doi: 10.1016/S2214-109X(19)30427-9.  PMID: 31708151 Free Article.
2.   Anemia and iron deficiency: effects on pregnancy outcome. Allen LH. Am J Clin Nutr. 2000 May;71(5 Suppl):1280S-4S. doi: 10.1093/ajcn/71.5.1280s. Review. PMID 10799402.
3.    Iron deficiency anemia in pregnant women.  Khuu G, Dika C.  Nurse Pract. 2017 Oct 18;42(10):42-47. doi: 10.1097/01.NPR.0000516124.22868.08. Review. PMID 28753164.
4.    UK guidelines on the management of iron deficiency in pregnancy.  Pavord S, Myers B, Robinson S, Allard S, Strong J, Oppenheimer C; British Committee for Standards in Haematology.  Br J Haematol.  2012 Mar;156(5):588-600.  Erratum in:  Br J Haematol. 2012 Aug;158(4)559.  PMID: 22512001.
5.    Iron Deficiency Anemia in Pregnancy.  Breymann C. Semin Hematol. 2015 Oct; 52(4):339-47.   doi: 10.1053/j.seminhematol.2015.07.003. Epub 2015 Jul 10.  Review. PMID:  26404445.

Note: The session is a self-approved group learning activity (Section 1) as defined by the Maintenance of Certification program of The Royal College of Physicians and Surgeons of Canada.


To register for the LearnTransfusion series, send an email to learn.transfusion@blood.ca with  “Weekly Transfusion Medicine Seminars” in the subject line. Include your name and complete e-mail address in the body of the e-mail, and confirm that you would like to register for the LearnTransfusion series. You will then receive weekly email notifications of upcoming series events with details on how to join the webinars (e.g., call-in number and a link to register for the webinar).

The LearnTransfusion series is the seminar component of the Areas of Focused Competency (AFC)-Diploma Program in Transfusion Medicine. The series, organized by Canadian Blood Services is also open to all practitioners in the field of Transfusion Medicine. Through a series of regular webinars, trainees and practitioners are exposed to various scientific, technical and clinical aspects of transfusion medicine.

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