AABB eCasts

Immunohematology Boot Camp: Clinically Insignificant High Incidence Antibodies (HTLA) (25EL-531)

When
Where
Virtual

Event details

Clinically insignificant high incidence antibodies, also known as high titer low avidity (HTLA) reacting antibodies, can be confusing and cause difficulty in antibody identification. This program will provide a lecture-based overview of the blood group antigens associated with these antibodies and the laboratory techniques that may be used to identify them. Case studies will also be presented to give practical tips to learners for managing this type of reactivity within a serologic investigation.

Presented by

Beth Meyer, MS, MLS(ASCP)CMSBBCM
Director/Moderator
Supervisor, Immunohematology Reference Laboratory, American Red Cross
Maryland Heights, MO

Janis R. Hamilton, MS, MLS(ASCP)SBB
Speaker
Manager, Immunohematology Reference Laboratory, American Red Cross
Detroit, MI

Learning objectives

After participating in this educational activity, participants should be able to:

  • Identify the antibody specificities that commonly display clinically insignificant high incidence antibody reactivity (HTLA-reacting antibodies) and describe the corresponding blood group antigen’s characteristics: Chido/Rodgers, Knops, Cost, JMH, Sda.
  • Discuss the serologic findings consistent with these antibodies and the investigational methods that may be used to identify them including enzyme and chemical red blood cell treatments, serum/plasma neutralizations, and titers.
  • Recognize patterns of reactivity for these antibodies and explain the next steps to take in serologic investigations by reviewing case studies.

Registration

Registration includes access to both the live and on-demand version of this eCast. Registration for the live eCast will close 1 hour prior to the eCast start time. If you register after this time, you will receive access to the on-demand eCast when it is available.

For additional information and to register as a single viewer or group, visit the AABB event webpage. Please note: Registration fees are required for AABB events.