… these assumptions:   The disease is caused by a circulating pathogenic substance.  The pathogenic substance can be efficiently removed from the … transfusion reactions. Some institutions also use plasma reduced RBC units in this population. In addition, for …

… therapy, the concentrate has the advantage of being pathogen-reduced and available in a freeze-dried, powdered form, … Hypocalcemia can lead to hypotension, impaired coagulation, reduced ventricular function and increased neuromuscular …