Journal Club: Tranexamic acid applications for reduction of bleeding

Presented by

Dr. Khalid Batarfi
Transfusion Medicine Physician Trainee
McMaster University, Hamilton

Learning objectives

1. Review tranexamic acid use in different clinical situations
2. Review the benefits vs. risks in use of tranexamic acid
3. Discuss some of the off-label uses of tranexamic acid

References

1. Gernsheimer TB, et al. Prophylactic tranexamic acid in patients with hematologic malignancy: a placebo-controlled, randomized clinical trial. Blood. 2022 Sep 15;140(11):1254-1262.
2. Siemens K et al. Antifibrinolytic Drugs for the Prevention of Bleeding in Pediatric Cardiac Surgery on Cardiopulmonary Bypass: A Systematic Review and Meta-analysis. Anesth Analg. 2022 May 1;134(5):987-1001
3. Ockerman A, et al. Tranexamic acid for the prevention and treatment of bleeding in surgery, trauma and bleeding disorders: a narrative review. Thromb J. 2021 Aug 11;19(1):54

Note: The session is a self-approved group learning activity (Section 1) as defined by the Maintenance of Certification program of The Royal College of Physicians and Surgeons of Canada.

Registration  

Closed

Appraisal

Closed

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The LearnTransfusion series is the seminar component of the Areas of Focused Competency (AFC)-Diploma Program in Transfusion Medicine. The series, organized by Canadian Blood Services, is also open to all practitioners in the field of Transfusion Medicine. Through a series of regular webinars, trainees and practitioners are exposed to various scientific, technical and clinical aspects of transfusion medicine.