AABB eCasts

Immunohematology boot camp: Titer method and clinical application


Event details

Antibody titrations can be helpful in-patient management in the setting of pregnancy, hematopoietic transplant, solid organ transplant, and in the work-up of complex antibody cases. Suzanne Davisson will focus on lab techniques for titrations and different applications of titrations, such as prenatal testing, DTT-treated plasma titrations for transplant, and identification of high-titer-low-avidity antibodies. Dr. Shainker will discuss the use of titers from the MFM perspective and how they use them to determine screening for fetal anemia. The speakers will discuss various titer techniques and their applications, provide more in-depth discussion of titer application in the prenatal setting and provide case studies.

Presented by

Suzanne M. Davisson, BS, SBB(ASCP)CM
Team Lead Laboratory Scientist, Immunohematology Reference Laboratory/HLA Laboratory, Versiti Indiana, Indianapolis, IN

Scott A. Shainker, DO, MS
The Annie and Chase Koch Chair in Obstetrics and Gynecology, Director, New England Center for Placental Disorders, Beth Israel Deaconess Medical Center
Assistant Professor of Obstetrics, Gynecology, and Reproductive Biology, Harvard Medical School, Boston, MA

Learning objectives

After participating in this educational activity, participants should be able to:

  • Identify uses of antibody titration.
  • Choose titration techniques that best match the clinical indication.
  • Choose the proper antibody titration technique/proper cells and interpret challenging cases.
  • Describe the application of antibody titers as it relates to screening for fetal anemia.


Registration includes access to both the live and on-demand version of this eCast. Registration for the live eCast will close 1 hour prior to the eCast start time. If you register after this time you will receive access to the on-demand eCast when it is available.

For additional information and to register, visit the AABB event webpagePlease note: Registration fees are required for AABB events.