Topic Teaching: Transfusion-Transmitted Infections: History and Recent Trends

Presented by:

Dr. Gilles Delage
Vice-President, Medical Affairs-Microbiology
Héma-Québec

Objectives:

1.    To enumerate the various infectious agents transmissible by transfusion and to communicate the risk of each to a prospective blood recipient.
2.    To enumerate the various tests used to screen blood donors for transfusion-transmitted infections.
3.    To describe the risk management approach when confronted with an emerging infectious agent.  

References:

1.    Katz L, Dodd R. ‘Transfusion-Transmitted Diseases’, in Transfusion Medicine and Hemostasis, Clinical and Laboratory Aspects, 3rd edition, Editors: Shaz B, Hillyer C, Gil M. 2018 Elsevier Inc., pp 437-453.
2.    Transfusion-Transmitted Infections: an Update on Product Screening, Diagnostic Techniques, and the Path Ahead.  Dean CL, Wade J, Roback JD.  J Clin Microbiol. 2018 Jun 25;56(7). pii: e00352-18. doi: 10.1128/JCM.00352-18. Print 2018 Jul. Review.  PMID:  29669792  Free PMC Article
3.    Pathogen Inactivation Technologies: The Advent of Pathogen-Reduced Blood Components to Reduce Blood Safety Risk.  Devine DV, Schubert P.  Hematol Oncol Clin North Am. 2016 Jun;30(3):609-17. doi: 10.1016/j.hoc.2016.01.005. Review.  PMID:  27112999
4.    Blood-Borne Pathogens: A Canadian Blood Services Centre for Innovation Symposium.  Walsh GM, Shih AW, Solh Z, Golder M, Schubert P, Fearon M, Sheffield WP.   Transfus Med Rev. 2016 Apr;30(2):53-68. doi: 10.1016/j.tmrv.2016.02.003. Epub 2016 Feb 23.   PMID:  26962008

Note: The session is a self-approved group learning activity (Section 1) as defined by the Maintenance of Certification program of The Royal College of Physicians and Surgeons of Canada.

To register for the LearnTransfusion series, send an email to learn.transfusion@blood.ca with  “Weekly Transfusion Medicine Seminars” in the subject line. Include your name and complete e-mail address in the body of the e-mail, and confirm that you would like to register for the LearnTransfusion series. You will then receive weekly email notifications of upcoming series events with details on how to join the webinars (e.g., call-in number and a link to register for the webinar).

The LearnTransfusion series is the seminar component of the Areas of Focused Competency (AFC)-Diploma Program in Transfusion Medicine. The series, organized by Canadian Blood Services is also open to all practitioners in the field of Transfusion Medicine. Through a series of regular webinars, trainees and practitioners are exposed to various scientific, technical and clinical aspects of transfusion medicine.